Which amino acids may aid wound healing?

Which amino acids may aid wound healing?

• A. Arginine and Glutamine.
• B. Lysine and Methionine.
• C. Glycine and Proline.
• D. Histidine and Cysteine.

Answer: (A)

Wound healing needs building blocks for new tissue, plus energy and immune support. Arginine and glutamine stand out because they help both sides of repair. Arginine acts as a precursor to nitric oxide, which improves blood flow to the wound and supports immune cell function. It also contributes to collagen synthesis indirectly by supporting the cellular environment needed for tissue repair, especially when the body is under stress. Glutamine is a major fuel for rapidly dividing cells involved in healing—fibroblasts that lay down new collagen, lymphocytes, and enterocytes lining the gut. It helps maintain nitrogen balance and supports immune defense and gut barrier function, both important for healing and infection prevention. While other amino acids like glycine and proline are important components of collagen, and cysteine or histidine have roles in various metabolic processes, the combination of arginine and glutamine has the strongest, more direct evidence for aiding wound healing across clinical settings, making it the best-supported choice.

Wound healing needs building blocks for new tissue, plus energy and immune support. Arginine and glutamine stand out because they help both sides of repair.

Arginine acts as a precursor to nitric oxide, which improves blood flow to the wound and supports immune cell function. It also contributes to collagen synthesis indirectly by supporting the cellular environment needed for tissue repair, especially when the body is under stress.

Glutamine is a major fuel for rapidly dividing cells involved in healing—fibroblasts that lay down new collagen, lymphocytes, and enterocytes lining the gut. It helps maintain nitrogen balance and supports immune defense and gut barrier function, both important for healing and infection prevention.

While other amino acids like glycine and proline are important components of collagen, and cysteine or histidine have roles in various metabolic processes, the combination of arginine and glutamine has the strongest, more direct evidence for aiding wound healing across clinical settings, making it the best-supported choice.